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ADEP addition resulted in increased MurAA levels, implying reduced ClpP-dependent proteolysis of the folded model substrate upon ADEP treatment of B. subtilis cells (Fig 3D).
In contrast to the unfolded polypeptide casein, no known folded model substrates including B. subtilis MecA, McsB, ComK, green fluorescent protein (GFP -SsrA, the N-end rule model substrate FR-linker-GFP -SsrAther natively folded proteins such as E. coli Grule, Trigger Factor and DnaK were degraded in vitro by ADEP-activated ClpP (data not shown).
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RosettaEPR increased the fractions of correctly folded models (RMSDCα < 7.5 Å) and models accurate at medium resolution (RMSDCα < 3.5 Å) by 25%.
In this study, a method to create a folded balloon model is presented and utilised to numerically model the accurate deployment of a stent in a realistic geometry of an atherosclerotic human coronary artery.
Referring to the receiver function of the F-net N.OSWF (see map in Fig. 4), Porritt and Yoshioka (2016) also proposed a complex folded slab model.
The folded balloon model adopted in this paper lacks the interaction with the catheter, which led to an overestimation of the dogboning effect during the expansion as also reported in Martin and Boyle (2013).
It is found that the folded core models with curved fold lines exhibit the best mechanical performances in compression and shear while the multiple layered models outperform the other folded core models in bending.
Furthermore, the folded core models are compared to a honeycomb core model with the same density and height.
This paper presents a parametric study on the mechanical properties of a variety of Miura-based folded core models virtually tested in quasi-static compression, shear and bending using the finite element method.
One is a cylindrical rubber balloon with a thickness of 0.5 mm and a diameter of 1.4 mm, and the other is a folded balloon modelled as a shell surface.
Fitting of the folded Skellam mixture model only used the 10702 SNPs in 3' UTR We fit the folded Skellam mixture model to the adjusted read pairs classified into the first Poisson mixture component, and only use SNPs on the 3' UTR.
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