Sentence examples for folded independently from inspiring English sources

Perhaps the two proteins are folded independently with more charged residues exposed and their conformation change during complex formation is very restricted, thus the two proteins prefer to interact in an electrostatic complementary manner.

The SCI is defined as the minimum free energy of the consensus folding structure divided by the mean minimum free energy (MFE) of each sequence in the alignment folded independently [ 48].

Although most of the cellular proteins can fold independently, HSPs are essential to efficiently facilitate the protein folding process [ 19].

Thus, p16C is the smallest ankyrin repeat module that is known to fold independently and, in general, we believe that the two-ankyrin repeat fold could be the minimum structural unit for all ankyrin repeat proteins.

Our studies suggest that the difference in kinetic folding pathways between α-lactalbumin and lysozyme can be explained by the difference in packing density between secondary structural elements and support the hypothesis that the structured regions in a protein folding intermediate may correspond to regions that can fold independently.

On the basis of preliminary proteolysis studies and predictions using a computer algorithm for identifying autonomous folding units, we have identified a fragment consisting of the third and fourth ankyrin repeats of p16, called p16C, that can fold independently, without the rest of the protein.

Dear Editor, Protein domain is usually defined as distinct, compact and stable protein structural unit that folds independently of other such units (Koonin et al., 2002).

One protein is generally composed of one or more domains (i.e. building blocks) that each might fold independently into a stable structure.

Several experimental [1] [3] and computational studies [4], [5] suggest that the folding of this enzyme is a three-state process in which first two monomers fold independently and then dock in the dimer native state.

These linking peptides do not function as stabilizing elements to the tertiary structure of the globular head, and thus provide ideal sites to truncate the globular head from the rest of HA1 such that it folds independently.

In contrast to the bI3 RNA, these RNAs are relatively small and contain well-characterized tetraloop-receptor elements that fold independently and accurately in the presence of magnesium ions [25], [33].