Sentence examples for fold upstream from inspiring English sources

This engineered degron is inactive in darkness due to the helical fold upstream of the cysteine-alanine motif and is activated by Jα helix unfolding.

12 When purified recombinant AMPK activity from bacterial cell lysates was measured, AMP stimulated the activity of AMPK by up to 10-fold and upstream kinases by up to 100-fold, and the combination of AMP with the upstream kinases by up to 1000-fold.

AcH4 also displayed allele-specific enrichment, in the range of 45- to 50-fold at VλR and ψVλ17; and 20-fold at most upstream sites in the ψVλ array.

The average radium concentration in estuary areas lined with mangroves was 2.5 times higher than the average concentration at the mouth of the estuary and 6.5-fold higher than upstream freshwater areas.

The GFP folding reporter assay [1] uses a C-terminal GFP fusion to report on the folding success of upstream fused polypeptides.

Htz1 peaks were associated with a transcript if they had downstream RNA signals >3-fold higher than upstream signals.

Also as expected, the mTOR inhibitor Rad001 decreased phosphorylation of mTOR (0 ± 0.01 versus 1 ± 0.1-fold vehicle) and p70 S6 kinase (0.02 ± 0.02-fold versus 0.1 ± 0.1-fold vehicle) without affecting upstream Akt.

Moreover, further increase of JUN/FOS signalling may occur through cooperation with Smad3 [ 50] because expression of this factor is also increased several fold as is the upstream regulator of Smad signalling, TGFBR2 and its ligand TGFB2.

In this context, it is of note that the 17-residue SecM "arrest sequence" has been used extensively to detect and analyze co-translational targeting or folding of inserts placed upstream of it; the elongation arrest is indeed subject to release when the folding or membrane insertion takes place near the ribosomal tunnel exit region27,28,29,30,31,42.

The average saline porewater exchange was ∼ 10-fold larger than the upstream surface freshwater inputs to the estuary.

The channel gradient is lower locally upstream of folds causing turbidity currents within the channel to decelerate and deposit the coarsest sediment load.