Exact(3)
For each target gene in each tested phenotype of the pooled analysis, a relative expression fold superior to 2 was considered as significantly differentially expressed [ 60, 61].
On the other hand, although the maximal dose recommended in adults is 600 mg for both mexiletine and carbamazepine, the expected therapeutic range of plasma concentration is in between 4 and 12 μg/ml for carbamazepine and 0.5 2 μg/ml for mexiletine, suggesting that bioavailability of carbamazepine is about 6 fold superior.
It is as active as imipenem or ertapenem against Gram-positive cocci (methicillin-susceptible S. aureus [MSSA] and coagulase negative staphylococci), but anti-Gram-negative activity is similar to that of meropenem, and two to three fold superior to imipenem [ 42].
Similar(57)
The sensitivity of this procedure, however, was two-fold superior to that of ELISA.
As an inhibitor of HepG2 cells (IC50 = 20 nM), 13 was 4-fold superior to 19.
Therefore, the brain uptake clearance ratio of [18F]-9 (2 mis/120 min) is 1.3-fold superior to [18F]-AV-45 [18F]-AV-45 [18F]-AV-45andof [18F]-Florbetaben is healthy micomparable
The gas transport layers are cost effective compared to current gas transport media (∼3× more expensive) especially considering their greatly reduced thickness, and several hundred-fold superior electrical and thermal conductivity.
The adaptive prey-size diet designed (MiACop) by combining stages of copepods (nauplii, copepodite and adult), rotifer and commercial nauplii of artemia was five-fold superior to the artemia/zooplankton diet all along the first 30 dph larvae culture.
The in vitro kinase inhibition results were verified by Western blot analysis, and indicated that compounds 3m and 3n were more than 75-fold superior in inhibiting T-loop autophosphorylation of Aurora-A (Thr288), compared to Aurora-B (Thr232) in HCT116 colon carcinoma cells.
In all cases where the CD28SA had been applied in vivo, and irrespective of additional in vivo treatment with SEB or anti-phlogistic therapy with Dex, the Treg cells recovered were five to ten-fold superior in suppressive activity as compared to Treg cells from naïve mice.
Moreover, conjugates demonstrated 3- to 14-fold superior cytotoxicity compared to that of irinotecan with IC50 value of 14.17 ± 1.273 μM.
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