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Holm, L. & Sander, C. Touring protein fold space with Dali/FSSP.
We probe the stability and near-native energy landscape of protein fold space using powerful conformational sampling methods together with simple reduced models and statistical potentials.
Among the many different objectives of large scale structural genomics projects are expanding the protein fold space, enhancing understanding of a model or disease-related organism, and providing foundations for structure-based drug discovery.
The goals of SG initiatives are to accelerate the process of protein structure determination, to fill in protein fold space and to provide information about the function of uncharacterized proteins.
Fold space is represented by a set of 280 protein domains spanning all topological classes and having a wide range of lengths (33 300 residues) amino acid composition and number of secondary structural elements.
The warp drive scenario got a boost when a NASA-linked lab announced that they thought they could sorta kinda fold space... if they could get enough strange matter (as in a few stellar masses' worth) and manage to stabilize it beyond the usual nanosecond life length.
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The folding mechanical characteristics, such as folding force, folding space and shape, are obtained by using the proposed model.
Simply cut multiple pairs of slits along the fold, spacing them evenly apart, until you create the number of tabs you need for your illustrations.
It's probably inevitable that the Keating Five scandal should re-emerge — and perhaps appropriate — but why are you wasting above-the-fold space with rumors of a romantic relationship?
Furthermore, it is proved that K has a Taylor series expansion at any given φ ∈ Hs(R), i.e., [formula] where Kn, the nth derivative of K at φ, is an n-linear map from the n-fold space of Hs(R) to C([−T, T]; Hs(R)) and the series converges in the space C([−T, T]; Hs(R)) uniformly for ||h|| ≤ δ for some δ > 0. Each term yn= Kn[hn] in the series solves a linearized KdV equation.
A cut above the rest Folded space ReprintsLittle, but not none.
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