Sentence examples for fold shift from inspiring English sources

The reciprocal mutations in PDE4B and PDE4D cause a 70 80 fold shift in selectivity.

Our label-free approach confirmed an 8 fold shift in affinity between Enzalutamide and Bicalutamide, and a 12 fold difference between ARN-509 and Bicalutamide (Fig. 3c).

QD delivery enhances T cell priming, leading to a 5 20 fold shift in the dose required to stimulate proliferation and a strong enhancement of IFN-γ production, compared to a standard immunization using equivalent amounts of free antigen (ovalbumin).

Indeed we found a number of genes with more than a 10 fold shift in expression levels.

The dashed line delineates the threshold value of a 1.5 fold shift that was interpreted as evidence of transcriptional differences.

Significantly, we observed a 3.6 and 4.4 fold shift in resistance in the Pfcam-I398F/P990R line and Pfcam-A211T line respectively, but no shift for other antimalarials.

injection potentiated morphine's antinociception and yielded a 14.6-fold shift in morphine's dose response curve.

Experimental results showed that under optimal conditions an eight-fold shift in the equilibrium conversion could be attained.

We next overlapped the Sequenza WES copy number segments bed file with our regions of interest and looked for any segment overlap requiring a log2-fold shift of ± 0.2 for gains and losses respectively in WES.

The two- to three-fold shift of the tyramine dose response curve (corresponding to a 22 mg increase in TYR PD30) observed in our study, after 7 days of administration, is consistent with the results of these earlier studies.

The K138R mutant showed a 1.3-fold shift of reaction specificity toward methanolysis compared to the wild type, while the V-95D, I53V, P-96S/F196Y, and Q128H/Q197L mutants showed shifts toward hydrolysis of 1.6 5.9-fold 1.6 5.9-fold