Sentence examples for fold shared from inspiring English sources

The distinct compact fold shared by these polypeptides may be useful in the design of molecules with desired pharmacological activity.

How the conserved kinase fold shared by all metazoan protein kinases can accomplish these diverse tasks in a specific and regulated manner is poorly understood.

In addition, despite the overall very similar fold shared by these helicases, the bound oligonucleotide molecules are not superimposable (data not shown).

The common fold shared by these proteins was termed the β-grasp, because the β-sheet appears to grasp the helical segment in this domain [ 7].

MazE, PemI, and their homologs have a swapped hairpin β-barrel fold shared by AbrB and SpoVT-type of transition state regulators (Coles et al. 2005).

A Sema domain, a PSI domain (so-called because it is present in plexins, semaphorins and integrins) and four IPT domains (immunoglobulin-like fold shared by plexins and transcription factors) make up the extracellular portion of c-Met.

Most of the archaeal histones have a single histone fold domain; however, there are a number of sequences that contain two histone folds, with the C-terminal histone fold sharing higher sequence similarity with archaeal histones with a single histone fold.

We also used MOTIF-EM to identify the conserved folds shared among dsDNA bacteriophages HK97, Epsilon 15, and ô29, though they have low-sequence similarity.

To optimise the compared methods more appropriately to predict stability changes in unseen proteins, we split the training set into 10 folds so that none of the folds shared homologous sequences (unseen-protein cross-validation).

It was clear from analyses of the data and relevant studies in the literature that some proteins adopting similar folds shared no other features indicative of an ancestral relationship ie no similarity in sequence motifs or functional properties and were therefore likely to be related through convergent rather than divergent evolution.

These 51 residue proteins, which adopt the helix-turn-helix homeodomain fold, share as few as 12 residues in common with their most closely related natural analog.