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All Infinium HD BeadChip markers have an average 15-18 fold redundancy, yielding low overall noise (average std dev log R ratios < 0.2) for copy number measurements.
Miapaca2 pancreatic cancer cells were infected with a lentivirus library containing ShRNA hairpins targeting 8600 open reading frames with 5 fold redundancy [29].
BACs were sequenced to 8 12 fold redundancy and assembled.
The survey covered a total set of 100 genes with at least three fold redundancy.
This genotyping system produces reproducible and robust data due to its 30 fold redundancy at each locus.
The BACs 220c16 and 231j9 were sequenced to 3.1 and 2.2 fold redundancy, respectively, using a shotgun strategy as described in Wilson et al. [ 43].
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Sequence-specific query oligonucleotides encompassing primer extension, ligation and universal PCR in highly multiplexed reactions 1536-plexx), two-colour landlling and redundant (∼30-fold redundancy of each bead type) feature representation were used to probe up to three different exonic sites per gene.
Each BeadChip has ~ 24,000 well-annotated RefSeq transcripts with ~ 30-fold redundancy.
You'll get this two-fold redundancy because you've got both flanks on each restriction site.
Here we report the DNA sequence of a diploid genome of a single individual, James D. Watson, sequenced to 7.4-fold redundancy in two months using massively parallel sequencing in picolitre-size reaction vessels.
Today, Celera says it has accumulated 15.9 billion bases of raw data, providing 6-fold redundancy, or enough to enable its bioinformatics crew to assemble the genome.
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