Sentence examples for fold reductions from inspiring English sources

In animal study, about two fold reductions in hyperglycemic level were achieved by SD compared to pure drug.

Significant 4 6 fold reductions in affinity for the endogenous agonists, epinephrine and norepinephrine were observed for receptors with the D191A mutation in the second extracellular loop.

These large fold reductions in affinity suggest that contribution of D292 extends beyond its likely electrostatic interaction with Lys4 in H3 and into structural organization of the N-terminus of the PHD1 for histone binding.

Pretreatment of the eyes of NZW rabbits with Y-27632 resulted in aggregate fold reductions (1 hour, 0.25-fold; 4 hours, 0.45-fold) of timolol maleate drug concentrations in intraocular tissues (aqueous humor, lens, and iris) versus eyes not receiving Y-27632 pretreatment.

Fold reductions were decreased in proportion with drug sensitivity in these cases.

Mice vaccinated with different gp63 DNA vaccine regimens showed comparable levels (1011 fold reductions in parasite load compared to PBS, p<0.001) of parasite clearance in spleen.

Sample sizes to detect 2-fold reductions from rates and risks observed since the mid-1990s are larger than recently reported case series.

The Leu308Val mutation resulted in 13-fold and 3-fold reductions in the inhibitory potencies of DCL and 3-bromo-5-phenylsalicylic acid (BPSA), respectively.

The replacement of Leu308 with an alanine resulted in 473-fold and 27-fold reductions in the potencies for DCL and BPSA, respectively.

Even though all of the patients treated in the Miravirsen trial were infected with genotype 1 HCV, three of the eight individuals at the highest dosage did not exhibit greater than 50-fold reductions in viral loads12.

The fact that not all patients responded to Miravirsen therapy (even at the highest dose, three out of eight patients did not exhibit greater than 50-fold reductions in viral loads), suggests that either host or viral factors influence treatment response.