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However, the NMR shifts for the ring-current shifted Hα and Hβ3 sites in Pro18 indicated a fold population (χF) of only 0.17 at 280 K and an extrapolated Tm below −9 °C.
Most striking is the population decline, observed during Last Glacial Maximum i.e. 23 to 19 kyBP [ 25] and Late Glacial Aridity i.e. 18 to 14 kyBP [ 26], followed by many fold population growth in a comparatively short period of time.
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A pseudo-two-state assumption was applied to derive the fold populations essential for the extraction of kF and kU values.
When BCSCs were compared benign SCs, IL-6 was elevated 20 fold in the CD49f−CD24−(MM) population, but a range of expression was detected in CD49f+CD24+ (PP) (10 to 10−4 fold) and CD49f−CD24+(MP) (102.5 to 10−2 fold) populations.
It identifies 10 countries in Africa that are likely to experience a many-fold population increase: Angola, Burundi, Democratic Republic of Congo, Malawi, Mali, Niger, Somalia, Uganda, Tanzania and Zambia.
In the context of HDSSs, it has been suggested that the resource-intensive active follow-up of individuals can only be justified if the results can be extrapolated meaningfully into the surrounding 100-fold population (5, 16).
This was mirrored by the inference by Bayesian skyline plot (BSP) of a two-fold population size increase occurring 15-20 Ky BP in this clade (data not shown).
Annealed substrate changes the partitioning of the ribozyme among the multiple folding populations.
Human MSC expressed Myf5 with up to a 30-fold population-dependent transcript level variation (data not shown).
Since sub-Saharan Africa only contains 11% of the world's population (5), this reflects a three-fold population-based risk for adverse effects of climate change among Africans compared with the global population.
Differences were much more pronounced between Lgr5lowKi67+ (four genes > twofold and 60 genes over 1.5-fold) and Lgr5lowKi67− (161 genes > twofold and 257 genes over 1.5-fold) populations (Fig 5C and D).
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