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As the result, we have found that the inhibitor showed about 13-fold lowered IC50 value compared with that of the corresponding monovalent peptide, thereby activating HIF-1α and leading to up-regulation of VEGF protein at the cellular level.
As shown in this study by modelling impaired diffusivity, more than 100-fold lowered diffusion coefficients were required to maintain spatial anisotropies during apoptosis execution in the reference scenario.
Folding lowers the statistical uncertainty in the phase bins as the number of counts increase.
However colon cancer death rate is ten fold lower in Mexico, South America and Africa as compared to the United States and Europe (Bray et al., 2002).
However, the sensitivity in PI mode was 10 20 fold lower than in negative mode.
Production of IL-6 by iNOS−/− MSCs was 5 fold lower than wt B6 MSCs.
F08A8.4 is expressed three fold lower in nhr-64RNAi worms than in WT worms.
However, the divergence observed among these strains was 0.1%, 35 fold lower than the expected divergence.
MMP activity was 3±0.06 fold lower in the cancer cells using gelatin zymography (Fig. S2).
This is about 2.5 fold lower when compared to the neurodegenerative diseases described above.
The yield of three of these mutants, Δ187 192, G217A, F338A, was several fold lower than WT Hhat.
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