The two fold dose increment that we did in this study does not seem to be necessary to achieve adequate plasma concentrations.
After more than 6-fold radiation dose reduction by simply lowering the tube current, we observed a good correlation between the mean measurement values in LD and the ULD (more than six fold dose reduction), but a high level of noise in the ULD images which did not allow sufficient calculation of brain perfusion maps.
Efficacy of the trimodal treatment was significantly greater than that achieved with bimodal- or individual treatments with potential for 10-50 foldosese reduction compared to that required for individual treatments.
Furthermore, it is good practice when using a calculator to mentally check the result to see if it is "ball-park" correct, in case of a typing error, such as a misplaced decimal point that could lead to a ten-fold dosing error.
It is also possible that students did in fact note that the acetaminophen dosage was too high, but decided not to mention it during the encounter or during the write-up as they may have thought that a several-fold dosing error was insignificant.
A two-fold dose escalation gave a 2.4-fold increase in the total AUC.
The greater immune response achieved by high expression was maintained over a 100-fold dose range.
At 22 d of age, all the experimental groups except for NC were challenged with 50-fold dose of Livacox T as a trivalent live attenuated coccidiosis vaccine.
β-Endorphin displayed only limited effectiveness in causing prolactin release when tested over this 30-fold dose range, compared to loperamide or fentanyl.
On day 18, all experimental groups except for the negative (group 1) were challenged with 10-fold dose of Livacox T™ to produce a mild coccidiosis infection.
Conversely, technologists had a great impact on radiation dose, both in terms of median and IQR, with DLP values varying from 580 mGy∙cm to 1,047 mGy∙cm, associated with an approximately ten-fold dose variation for the same kind of CT examination (lowest and highest observed values: 202÷1,970 mGy∙cm, P < 0.001).
