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"fold difference" is a correct and usable phrase in written English.
It is typically used in scientific or technical contexts to describe the ratio or difference between two values or quantities. Example: The researchers found that there was a ten-fold difference in the strength of the new medication compared to the old one.
Exact(30)
Fold difference was calculated as 2−ΔΔCt.
Method and apparatus for determining fold difference significance.
Fold difference in fluorescence from T0 was calculated and plotted over time.
Additionally, another thaumatin gene was found to have high expression fold difference of 22.5 × .
Fold difference was calculated from the estimated log ratio.
Fold difference was calculated as 2 Ct input -Ct(ChIP)).
Similar(30)
There was a two-fold difference in the success of different areas.
The GFP intensities measured in the distal segments differed from those in proximal segments by a minimum of a 15-fold difference to a maximum of a 72-fold difference (mean = 39-fold difference; n = 10 nephrons; Figure 1C).
There is a 15-fold difference between prevalence in black men compared with white men.
And yet there's a 30-fold difference in our life span.
"There was at least a 10-fold difference between the hepatitis patients and the controls," Dr. Alter said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com