Sentence examples for fold closely from inspiring English sources
The fold closely resembles that of NAT from Salmonella typhimurium, with a common catalytic triad and domain structure that is similar to certain cysteine proteases.
We have determined the crystal structure of the T4 UvsX recombinase, and the overall architecture and fold closely resemble those of RecA, including a highly conserved ATP binding site.
Alignment of beta-chemokine amino acid sequences revealed the presence of several highly conserved basic amino acids, and molecular modeling predicted that the side chains of three of the basic amino acids fold closely together in MIP-1alpha.
This soluble form of CLIC1 consists of two domains: the N-domain possessing a thioredoxin fold closely resembling glutaredoxin and an all α-helical C-domain, which is typical of the GST superfamily.
The B. subtilis YphP is a member of an unusual oxidoreductase superfamily of enzymes (DUF1094) with a natural CXC motif within the active site and a tertiary fold closely reminiscent of the thioredoxins.
Furthermore, the content and orientation of p7 helical domains were reminiscent of those proposed by membrane ssNMR, 26 suggesting that MeOH induced a protein fold closely resembling that formed in the bilayer.
Consequently, we conclude that the peptide core sequence does not correspond simply to the lower hinge sequence P232ELLG236 of IgG1, but in contrast is comprised of several noncontiguous determinants folded closely into a scaffold of 8 amino acid residues that are required to make the peptide functional.
The cPPR-Telo1 protein adopted an overall fold that closely mimicked other designed PPR structures21, 24, 29 (Fig. 2d, e), where the two helices of each repeat, helix a and helix b, form a hairpin and these hairpins stack upon each other to form a right-handed superhelix.
When Dusp3 was normalized to 18S or the geometric mean of stable reference genes (Fig. 2D), fold changes closely approximated those shown for raw Dusp3 without normalization (Fig. 2C), where gene expression was significantly different from untreated controls at each point following 3 hrs post-H2O2 exposure.
Divergence, while extreme in the N-terminal tail of CENP-A, is prevalent even within the C-terminal histone fold of closely related species.
