Sentence examples similar to fold capacity from inspiring English sources

ATF6-mediated transcriptional induction of ER-localized molecular chaperones and folding enzymes can improve the ER folding capacity, contributing to the maintenance of ER homeostasis in mammals (Yoshida et al., 1998).

In S. cerevisiae, folding capacity is increased via transcriptional up-regulation; in S. pombe the folding load is decreased and the ER is restructured.

His systems, which are being tested in Tokyo by NTT DoCoMo, Japan's leading wireless operator, typically achieve a five-fold capacity improvement with eight antennas.

The response is adaptive, such that UPR activation triggers reductions in protein synthesis and enhancements in ER protein-folding capacity and ER-associated protein degradation.

The aggregate formation was not caused by a dysfunctional ER quality control mechanism or an intrinsic limitation in protein folding capacity.

While activation of PERK attenuates protein translation thereby decreasing protein reloading of the ER, IRE1 and ATF6 concertedly activate UPR-specific transcription to increase the ER folding capacity and function.

Spliced Xbp-1 (Xbp-1s) is an important regulator of ER folding capacity [19], [20].

Initially, UPR is an adaptive response in which the cells attempt to overcome the accumulation of misfolded proteins through augmenting protein folding capacity.

The protein folding capacity of the ER is directly affected by different environmental factors including the redox status of the cell, ER calcium content and ATP levels.

This in turn raises the question of whether Tat can overwhelm the protein folding capacity of the ER and induce the unfolded protein response (UPR) pathway [29].

The ER is a specialized intracellular organelle whose protein folding capacity is dependent on maintaining a relatively oxidized environment and high calcium concentrations required for chaperone molecules [45].