Sentence examples for fold alone from inspiring English sources

Our approach successfully tested the contribution of each surface-exposed loop in the trypsin fold alone and the cooperativity of their combinations towards building the substrate selectivity and Na+-dependent allosteric activation of the protease domain of human coagulation factor Xa into a bacterial trypsin.

Interestingly, cotransfecting both menin and Cdx4 with reporter pE yielded an additive activation of the reporter expression by 3.5 fold higher than either menin (1.3 fold) or Cdx4 (2.5 fold) alone (Fig. 5B).

Thirdly, we agree with the reviewer that similar structural fold alone does not provide sufficient evidence of common ancestry [ 75].

The remaining 13 genes analyzed here are restricted to specific mantle territories and are expressed discontinuously along the length of the mantle; either in the inner fold alone, the inner mantle fold and the anterior crease of the outer fold, the anterior crease of outer fold alone, or the anterior zone of the outer fold the mantle.

Decreased VEGF staining was observed in tumors treated with Noscapine (150 550 mg/kg/day) in dose dependent manner and combination (0.44-fold) compared to tumors treated with Doxorubicin (0.21-fold) or Noscapine 300 mg/kg/day (0.1-fold) alone (Fig. 6A and 6C).

Simply put extrinsic folding alone does not, by definition, change the surface: rather it changes how it is embedded in space.

Available evidence, however, neither supports the notion that stepwise folding alone drives translocation nor explains the efficient secretion of the intrinsically disordered RD domain or polypeptides that fold in the periplasm.

Thus, even within these two folds alone, a remarkable structural and functional complexity had been attained before the fully-fledged RNA-protein machinery of translation resembling the modern one has evolved.

Moreover, combination treatment increased pancreatic insulin content by 2.2-fold (alogliptin alone, 1.3-fold; pioglitazone alone, 1.6-fold), with no significant changes in body weight.

Combination treatment exhibited a complementary effect, increasing plasma insulin levels by 3.2-fold (alogliptin alone, 1.6-fold; pioglitazone alone, 1.5-fold) and decreasing glycosylated hemoglobin by 2.3% (alogliptin alone, 1.0%; pioglitazone alone, 1.5%), and non-fasting and fasting plasma glucose by 37%and62%2% (alogliptin alone, 17% and 24%; pioglitazone alone, 30%and45%5%), respectively.

In NB4 cells, the activation of caspase was enhanced from 3.5-fold (ATO alone) to 5.5-fold (ATO+ATRA).