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This chapter summarizes efforts to develop superior second-generation HIV protease inhibitors, particularly focusing on improvements in the pharmacokinetics and dosing schedules of clinical candidates.
Implementations of the described strategy in disease treatment scenarios include intravenous rather than oral drug delivery, focusing on improvements in pharmacokinetics, drug half-life and methods to aid slow drug release such as pegylation and liposomal delivery49.
Sanders accused reporters of being consumed by "petty palace intrigue" — stories about personnel moves and internal West Wing squabbles — instead of focusing on improvements in the economy and the administration's campaign against terrorist groups.
In addition, unlike most previous studies focusing on improvements to HS algorithms, SSWCHS modifies the memory structure itself.
The company says that, going forward, it's focusing on improvements to its core product, mobile shopping companion, Slice, instead.
Hello Games also took the opportunity to address negative feedback for the game, noting that they've followed the "intense and dramatic" discussion around their title but that they're focusing on improvements rather than on wading into the debate.
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Focusing on improvement of assistance and care services has the potential to substantially improve PWPD's QoL.
It has to be deliberate, dedicated time spent focusing on improvement.
The consternation for many arises from the apparent conflict between focusing on improvement while being faced with apparently overwhelming circumstances.
Further research is required in different populations and also focusing on improvement in patient outcomes.
Hence, it is more important to focus on patient physiology i.e. overcoming the inter-compartmental resistance rather than focusing on improvement of RRTs.
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