While conducting experiments focused on discerning the mechanisms of this process in 1981, Yanofsky noticed that the cell was able to sense how much tryptophan was present and alter the transcription process accordingly, halting it if necessary.
Future work will focus on discerning if this association is attributable to anesthetic exacerbation of membrane potential dissipation caused by selective impairment of complex I subunits that contribute to proton gradient flux.
In the last decade, evolutionary biologists have focused on discerning the mechanisms leading to reproductive isolation, and the field has witnessed major advances in determining the relative contribution of historical geographic barriers to diversification thanks to the possibility of linking geological and phylogenetic data [ 9].
Much of the statistical effort in analyzing CNAs has focused on discerning copy number at each location within individual tumors (Hupe et al., 2004; Olshen et al., 2004; Venkatraman and Olshen, 2007), and in handling the potential contamination of normal tissue in tumor samples (Sun et al., 2009).
(The title sounds strange, but many big companies now have executives focused on discerning the future).
Social interactions are focused on discerning how actors' pasts and anticipated rewards mutually influence their choices, conduct, and social relations in a group (Blau 1964).
Ethnographic research on the Placencia Peninsula in Belize focused on discerning perceptions of acceptability for the recovery of resources such as energy and nutrients from wastewater, local perceptions of health risks and benefits of such recovery, as well as how economic and environmental advantages of these processes intersect with local demands.
The approach of Naciff et al. is complementary to ours: They sought to develop a transcriptional profile "fingerprint" as evidence of gestational exposures and we focused on discerning potential modes of action reflecting biochemical characteristics.
Efforts to understand the recent rise in obesity focus on discerning the relative contributions of, or interactions between, genetic and environmental factors in adulthood [6], [7], [19], [23], [24].
Today's state-of-the-art prediction methods focus on discerning disease-causing variants from the background variation.
