Sentence examples for focused screening from inspiring English sources

A series of structure based drug design hypotheses and focused screening efforts drove improvements in the potency and lipophilic efficiency of tetrahydro-pyrazolopyridine based ERK2 inhibitors.

A series of structure based drug design hypotheses and focused screening efforts led to the identification of tetrahydropyrrolo-diazepenones with striking potency against ERK2 kinase.

Protein-ligand docking in BRD4(1) was used to purchase a small, focused screening set of compounds possessing a large variety of core structures.

A novel series of monoamine reuptake inhibitors, the 1-amino-3- 1H-indol-1-yl -3-phenylpropan-2-ols, have been discovered by combining virtual and focused screening efforts with design techniques.

Given the challenges involved in GPCR ligand discovery; in particular, the need to screen a large chemical space, one efficient approach for identifying hits would be to design or select focused screening libraries to reduce the workload.

Some of the patients selected through this process should be pointed towards more focused screening by specialized imaging techniques.

5 One approach for T2DM screening would be to focus screening on the disease only.

We subsequently integrated more refined bioassays to focus screening efforts on individual organs or targeted biological pathways.

The resulting overlays inspired a focused screen of 6-substituted azabenzimidazoles against TBK1/IKK-ε.

More recently, additional, more focused screens have entered the picture, with data also available through the web site.

Ms. Bullock, a star who tries harder than most to be a likable everywoman, doesn't shrink from portraying her character's nasty, imperious side, and these scenes feature some of the most focused screen acting of her career.