Sentence examples for focused screen from inspiring English sources
Ms. Bullock, a star who tries harder than most to be a likable everywoman, doesn't shrink from portraying her character's nasty, imperious side, and these scenes feature some of the most focused screen acting of her career.
The resulting overlays inspired a focused screen of 6-substituted azabenzimidazoles against TBK1/IKK-ε.
Indeed, a focused screen of pharmacological compounds that ameliorated the dnj-14 lifespan and neuronal defects identified the polyphenolic molecule resveratrol, which has been shown to be neuroprotective in a range of animal neurodegeneration models [71].
Comparing the data from the DNA repair focused screen to that generated in genome scale screens, it is clear that by focusing on a smaller set of genes in this targeted screen, we were able to reproduce some of the results from previous screens.
We undertook a focused screen of chemical compounds that exhibit protein aggregate-binding properties, such as Thioflavin T (ThT) and curcumin, widely used to stain these aggregates in post-mortem tissues of neurological disease affected individuals.
Starting from a hit identified by focused screening, 3-aminopyrrolidine factor Xa inhibitors were designed.
Compound 1 was discovered from focused screening of serine protease-directed compounds from our internal collection.
Here, we describe a focused screening of adenosine derivatives using X-ray crystallography.
More recently, additional, more focused screens have entered the picture, with data also available through the web site.
If the structure of the biological target is known a focused screening library could be designed, for example, through docking simulations.
A series of structure based drug design hypotheses and focused screening efforts drove improvements in the potency and lipophilic efficiency of tetrahydro-pyrazolopyridine based ERK2 inhibitors.
