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More advanced therapies that target focused pathways (anti- TNFα [ 10]) and reduce -but do not eliminate- this type of side effect are extremely costly, whereas traditional approaches receive controversial favour and lack molecular evidence [ 11].
By using IPA to analyze differentially expressed gene sets, we found focused pathways enriched in metabolism, tissue development, gene expression and cell cycle along with other immune-related pathways preferentially enriched in resistant chickens.
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However, due to limitations in the concepts and techniques, these have relied on a focused, pathway-oriented view.
This program provides a pathway for students interested in a data science focused pathway for an interdepartmental major in Statistical Science and Computer Science.
Focused pathway analysis also revealed that miR-218 may regulate genes directly and indirectly related to MYC and SRC, two well characterised oncogenes [20], [21], [63], [64], [65].
However, not all metabolites in a focused pathway can be simultaneously measured, and the measured metabolite concentrations are not yet sufficiently accurate for the construction of a precise mathematical model, which is due to the following several factors.
We found 32 paired pathways with AUROC > 0.90 between BC and NS, but we focused on pathways with the best 10 AUC.
The majority of previous studies on PTB have focused on pathways contributing towards intrauterine infection [30], ignoring the potential contribution of other pathways such as decidual hemorrhage.
The CO2 brine contact area is maximized within the sinuous and focused flow pathways that could increase dissolution.
The above-described results focused on pathways expected to be targeted by the B19R deletion and restoration of replication competence.
We focused on pathways which are activated by SCF induced phosphorylation of Tyr719 on c-KIT, which is essential for PI3K signaling [7].
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