Sentence examples for focused pathway from inspiring English sources

Focused pathway analysis also revealed that miR-218 may regulate genes directly and indirectly related to MYC and SRC, two well characterised oncogenes [20], [21], [63], [64], [65].

Mouse cell stress focused pathway arrays in a 96-well plate format (PAM-003A), compatible with an ABI 7000 real-time PCR machine, were used to assay cell stress gene expression (3 comparisons for YFP-16 and 3 for wild-type controls, each comparison composed of pooled whole spinal cord tissue from 3 individual 2 month old mice).

However, not all metabolites in a focused pathway can be simultaneously measured, and the measured metabolite concentrations are not yet sufficiently accurate for the construction of a precise mathematical model, which is due to the following several factors.

The purpose is not to establish optimally fitting models but to identify how the unmeasurable data of metabolites located in a focused pathway probably behave, which time-series data within the dataset may be inconsistent with the understanding of pathway, as well as which data within a large dataset are probably reliable and which, if any, are most likely imprecise.

The in-depth qualitative study across five English NHS Trusts draws attention to and deepens our understanding of the complex processes that can be involved in making a treatment decision, and examines the appropriateness of a linear, medically focused pathway underpinned by strong time-based incentives.

However, due to limitations in the concepts and techniques, these have relied on a focused, pathway-oriented view.

By using IPA to analyze differentially expressed gene sets, we found focused pathways enriched in metabolism, tissue development, gene expression and cell cycle along with other immune-related pathways preferentially enriched in resistant chickens.

More advanced therapies that target focused pathways (anti- TNFα [ 10]) and reduce -but do not eliminate- this type of side effect are extremely costly, whereas traditional approaches receive controversial favour and lack molecular evidence [ 11].

A more focused KEGG pathway analysis of our data indicates that MYCN binds upstream to a number of genes in the WNT signalling pathway.

An example would be the Kimmeridge Clay Formation (source) – Hugin Formation/Paleocene/Eocene sand (carrier/reservoir) petroleum systems of the Tertiary reservoirs in the Viking Graben, North Sea,[36] where many reservoir volumes of oil have been charged through a single focussed pathway.

Otherwise, if the clustering is guided and valine biosynthesis is chosen as a focus pathway, MetaViz efficiently represents it.