Initially, attention focused on specificity and affinity, with the selection of mAbs being based primarily on their ability to inhibit tumour cell growth in vitro.
While SI and KLAS presented very similar values - with KLAS showing a slightly better result - ARH was more focused on specificity.
Following this exercise, sensitivity of the expanded Approach 3 was improved: 0.581 (0.558 – 0.605) compared to 0.48 (0.456 – 0.504) for the original Approach 3. The specificity of the updated Approach 3 was reduced: 0.558 (0.527 0.58989) compared to 0.62 (0.59 – 0.65) for the original Approach 3. Changes to the algorithm focused on specificity also can be identified and implemented.
Hereafter, we focus on specificity of impacts (i.e. skew in performances across affected victims isolates).
A quality pre-screening test will focus on sensitivity while a quality serological test will focus on specificity.
When focusing on specificity, SplicingCompass was the clear winner followed by ANOSVA, KLAS, ARH and SI, all ranging on the second place.
It is important that future efforts also focus on specificity issues including possible off target effects such as unspecific trans-splicing, and cryptic cis-splicing or undesirable translation from within the RTM (Gruber et al., 2013, Monjaret et al., 2014).
Since then, most ecologists, biological control practitioners and regulators tend to focus on specificity not primarily because of its link to effectiveness but because it lessens the possible ecological risks associated with the introduction of natural enemies, often non-native, in the environment.
Our present study thus focused on the specificity of NF on three levels: band specificity, cognitive specificity, and baseline specificity.
The third analysis focused on the specificity of the influences of advance quizzing and review by testing whether the interventions would also predict the performance of the first-year students in the "Introduction to Perception" course.
