Sentence examples for focused on specific pathways from inspiring English sources

Some of the drug companies most involved in the search are small enterprises, focused on specific pathways or aspects of brain biochemistry.

Others have focused on specific pathways or loci (e.g., cancer sites [ 13], specific genes [ 11, 14], low numbers of CpGs across the genome [ 15]), or restricted their analysis to certain chromosomes [ 16, 17].

The identification of new genetic mutations as viable markers for therapeutic development is driving researchers and clinicians to focus on specific pathways for targeted therapies.

The former focuses on specific pathways and cellular functions that have been related to or are of special interest with respect to the particular physiological conditions.

In the words of Hannun and Obeid in a recent review: "First and foremost, the 'Many Ceramides' approach negates the current prevailing paradigm that ceramide can be understood in terms of regulation and function as a single entity... at the very least mechanistic studies on ceramide function and regulation should focus on specific pathways of formation".

Previous experiments, studying the operational mechanics of FFLs focused on specific biological pathways, such as metabolic pathways or signal transduction pathways, or involved the interaction of TFs alone (without the input of miRNAs).

To date, most research on dietary amino acid metabolism has been directed toward the analysis of metabolic adaptation to diets deficient in both energy and amino nitrogen [ 22– 25] or has focused on specific regulatory pathways.

Most attention has focused on specific nutrient regulatory pathways, in which a nutrient regulates its own transport and metabolism.

Reasoning that a smaller scale, targeted screen might provide better focus on specific pathways of interest, we screened an siRNA library targeting DNA repair genes for effects on HIV replication.

Also, some of these methods focus on specific pathways, and thus are limited to expansion to the whole metabolism.

In contrast to such large-scale systems biology approaches, targeted system models that focus on specific pathways may help to study how specific exosome content may change signal transduction processes in the target cells.