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In the first steps of the I-MPOS endeavor, though, one needs to be particularly cautious and focus on variants known to be pathogenic based on clinical experience.
In general, conclusions have been made on the basis of the standard form of each model, while in the present work we focus on variants of the common Delayed Detached-Eddy Simulation (DDES) approach, in order to demonstrate its sensitivity to commonly varied aspects of its usage.
Genome annotations and laboratory data can specify TSS locations, allowing researchers to focus on variants situated with functionally relevant spatial localization.
Further fine mapping and functional studies of 8q24 and colorectal cancer should focus on variants in high LD with this narrow region.
We focus on variants occurring in cis with target genes, as opposed to those in the splicing complex (in trans), leading to abnormal splicing.
The following sections highlight methods that researchers can use to focus on variants located within cis-regulatory elements, in particular TFBSs.
Similar(54)
SLC22A5 has previously been reported to be associated with IBD25, whereas previous psoriasis reports relating to chromosome 5q31 have focused on variants mapping to the IL13 gene.
The majority of genetic studies in the transplantation field have focused on variants in candidate genes, while genome-wide association studies (GWAS) and exome sequencing have just begun to be used in this field.
We study the reliability and performance of state-of-the-art iterative eigensolvers on large quantum dots and wires, focusing on variants of preconditioned CG, Lanczos, and Davidson methods.
When not fixated on bond-market anxieties, proponents of fiscal austerity have focused on variants of the "crowding out" argument that a high and rising government debt crowds out private investment and reduces economic growth.
First, we focused on variants in conserved regions.
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