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We also observed Beclin 1 S90 phosphorylation in response to other stress stimuli (data not shown), but chose to focus on starvation, given the crucial physiological importance of starvation in autophagy induction.
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While this manuscript focuses on starvation-induced autophagy and starvation-induced Beclin 1 S90 phosphorylation, we have also found that Beclin 1 undergoes S90 phosphorylation in response to several other autophagy-inducing stress stimuli.
In this study, we focus on the starvation-induced first larval stage (L1) diapause [ Additional File 1].
We propose that the bias towards the initial response is due to prior research almost exclusively focusing on the starvation response without considering recovery.
In this study, we focus on amino-acid starvation that leads to the formation of a novel, non-membrane bound cytoplasmic stress assembly that contains ERES components and that we call 'Sec bodies' [ Figure 1A and (Zacharogianni et al., 2011)].
Tuning out is adaptive, he says — it helped our hunter ancestors to focus on their prey and avoid starvation.
The proposed system does not focus on aborting the jobs and starvation.
With the world focused on the widespread starvation in Madaya, Bashar al-Assad's government has reportedly tightened its blockades of other areas, including Eastern Ghouta.
The effect of starvation on brain function impairs set-shifting – the ability to think flexibly and to multi-task instead of focusing on one thing – and the ability to read other people's minds.
It was humiliation, on starvation wages.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com