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Theoretical analyses are performed and numerical results are then presented with a focus on signalling loads to compare the two proposals and to demonstrate that the designs can largely meet the requirements on desired signalling performance.
The remaining parts focus on signalling molecule drug targets and immunotherapy in turn, with each part being further subdivided into chapters with a much narrower focus.
Similar(58)
Thus, one approach to examine GPCR signaling is to focus on signaling through one of the alpha subunits [36].
In particular, the CPCM combines understandings of biological circuitry — along with engineering, computational, and mathematical techniques (as well as genomic ones) — to focus on signaling networks and pathways that are aberrantly regulated in cancer cells.
It's our last week, and we're going to focus on signaling today.
Here, we will focus on signaling pathways in which kinases are activated by phosphorylation in series.
We have been among the pioneers in the field, with a primary focus on signaling studies [10] [13].
By design, expertly compiled pathway maps tend to focus on signaling cascades – bearers of core functionality.
Presentation of potential Pax3 target genes focuses on signalling pathways and on transcriptional regulation.
We however note that AlzPathway focuses on signalling pathways, whereas PathNER also extracted a number of metabolic pathways.
Focusing on signaling response to the secreted morphogen Hedgehog (Hh), we used RNA interference (RNAi) and a quantitative cultured cell assay to systematically screen functional roles of all kinases and phosphatases, and subsequently 43% of predicted Drosophila genes.
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