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For this reason, most studies focus on inducing stem cells, such as embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), hepatic progenitor cells (HPCs), and mesenchymal stem cells (MSCs), to differentiate into hepatocyte-like cells (HLCs) in vitro.
Using hepatocytes as an experimental system, his lab explores cell lineage conversion with particular focus on inducing non-hepatic cells to form functional hepatocyte-like cells.
Since AIFs are a complexion type that will have atomic structure and properties which are unique compared with normal, clean grain boundaries, we focus on inducing and characterizing these features in a nanoscale grain structure.
One approach is to focus on inducing downstaging and subsequent operability (Wilkowski et al, 2006).
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The Tissue Chip Project addresses this problem through the engineering of living tissues outside of the human body, hence the term "tissue chip". In conjunction with this project, Hannah's research focuses on inducing injury on these 3D-engineered blood vessels and studying the inner lining, known as the endothelial layer.
We excluded: a) review articles; b) case reports; c) experimental studies other than animal studies (for example, cell culture, isolated organs); d) studies focusing on induced circulatory arrest (for example, for aortic arch surgery).
Indeed, targets can either focus on factors inducing hepatic steatosis or intrahepatic mechanisms involved in glucose or lipid metabolism.
Strategies might focus on (i) inducing the MFBs "inactive" (overturn the phenotype back to fibroblast and thus circumvent the electrical coupling) or (ii) targeting these cells, pharmacologically or genetically, for radically hyperpolarization [ 9, 85].
Bone morphogenetic protein (BMP -based tissue engineering has focused on inducing new BMP -basedientissue
Roots up-regulated fewer genes and focused on inducing antioxidant and enhancing photosynthesis related genes.
Roots up-regulated fewer genes and focused on inducing antioxidants and enhancing photosynthesis.
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