A further chapter focuses on immunity and cell killing.
Therefore, we and other authors have suggested an indirect approach focused on immunity traits (ITs) [ 3, 7, 8].
However, achieving and maintaining polio eradication requires permanently stopping and preventing transmission, which requires a focus on population immunity to transmission, not a focus on population immunity to disease.
Also in atopic dermatitis the current emphasis is now moving away from an exclusive focus on adaptive immunity as the primary cause, towards local responses in the epithelium and quality of epidermal barrier function[1], [27].
Given our laboratory's focus on innate immunity, we chose to further investigate the effects of S-palmitoylation on the activity of TLR2 in primary cultured DCs.
Therefore, the limited overlap between InnateDB and other databases is intentional, avoids redundancy and reflects the database's focus on innate immunity.
In this study we focus on tumor immunity and melanoma to demonstrate the ability of this strategy to identify and grade the magnitude of the immune component of patient expression profiles.
Mechanistic proposals for disease pathogenesis have focused on adaptive immunity, particularly immune responses directed against myelin constituents.
The study focused on innate immunity, because disturbances in innate immunity could explain an increased susceptibility to infectious agents.
Importantly, this focus on one's body and immunity in the face of seemingly inevitable infection accentuated health individualism, encouraging members of the general public to focus on their body's abilities to resist and cope with infection.
The fact that ASFV has adapted to infect both mammalian macrophages and an invertebrate tick host suggests that this virus may have evolved immune evasion genes focused on innate immunity, more specifically, for manipulation of the Toll-like receptor (TLR) signaling system, which is conserved in both mammals and arthropods.
