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This new irradiation method could be useful for any brain disease where extremely precise focal tissue destruction is required.
On the other hand, only live B. pilosicoli induced significant expression of IL-8, suggesting that induction of this gene may be involved in the process of generating the focal tissue damage and colitis that can occur in vivo.
We speculate that prolonged localized congestion caused by AVF lead to focal tissue fibrosis.
The selected dyads were defined as the stable nucleosome dyads in the focal tissue type.
This likely reflects our RNA-seq approach, rather than any intrinsic property of the focal tissue or taxon.
Necrotic areas or non-enhanced regions were common, but focal tissue necrosis was a unique event after radiation therapy.
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The presence of retained and diseased focal tissues requiring removal remains poorly understood.
Therefore, targeted treatment delivered to the index lesion while sparing the rest of the gland may be a rational approach in men with intermediate- and low-volume, high-risk PCa that has disease suitable for a focal tissue-preserving approach.
This genome-wide study was performed to elucidate the transcriptome response of the ischemized focal tissues of the rat brain to the action of Semax in vivo.
We next shed light on the patterns found in Figure 4 by plotting the ratio of expression levels for genes in both focal tissues relative to that in the composite tissue (using the NOISeq RPKM analysis).
We do acknowledge that PWBC can reveal only a portion of the total gene expression information and that profiling it in other focal tissues like adipose and liver might reveal complementary genomic information.
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