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All three lesions were morphologically similar to each other and revealed focal disruption of PRs (Fig. 4: lesion 15).
Bottom right (lesion 15): focal disruption of photoreceptor IS/OS junctions with thinning of the ONL, unchanged over a period of 6 months.
A ruptured bulla will demonstrate focal disruption or discontinuity of the wall leading to air leak into the pleural cavity (Fig. 12).
An 'ulcer-like projection,' the radiological finding of a focal disruption of the surface of the aortic wall from the true lumen into the thrombosed false lumen, is identified at the mid ascending aorta (arrow).
SD-OCT images from their initial (pre-treatment) presentation demonstrated thickening and hyperreflective nodularity of the choroid-retinal pigment epithelium (RPE) complex, with focal disruption of the overlying photoreceptor inner segment-outer segment junction in the areas corresponding to the retinal lesions seen on clinical examination.
In the same eye, further towards the inferior arcade, there was another lesion with focal disruption of the RPE; the lesion seemed to be pulled (dragged) outwards with back shadowing, and there was an associated focal choroidal thinning (Fig. 4: lesion 2).
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Of the 220 cases with 5698 duct cross-sections examined, 94 showed disrupted myoepithelial cell layers with 405 focal disruptions.
Of the total cases and cross-sections examined, 94 (42.7%) cases contained a disrupted myoepithelial cell layer with a total of 405 (7.1%) focal disruptions.
These preparations also demonstrated focal disruptions of the tight-junctions, as shown by occludin staining, and the presence of infiltrating cells with small nuclei on the apical side of RPE cells (Fig. 5c4) which were not found in control eyes (Fig. 5c3).
There were pronounced focal disruptions in the aortic intimal layer of the rats fed heated oil.
A subset of pre-invasive and micro-invasive tumors contained focal disruptions in their ME cell layer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com