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Interlobular bile ducts were affected by destructive lesions with focal destruction of basal membrane by inflammatory cells, occasionally migrating within the biliary epithelium.
Several neuropathological findings associated with human and experimental hydrocephalus revealed focal destruction of the ependyma, changes in the cerebral vasculature, and ensuing damage to axons and oligodendrocytes around the ventricles [13], [28].
There was focal destruction of bile ducts and presence of intraepithelial neutrophils suggestive of cholangitis.
The FFL initially caused focal destruction of the cortical layers on the day of birth.
In 11 lesions there was contact with the cortex and in one lesion there was focal destruction of the cortex.
After World War II, use of DDT against malaria vectors and focal destruction of Leishmania spp. infected dogs is thought to have reduced ZVL on Crete (3 ).
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(iii) Photomicrograph (original magnification, ×20; haematoxylin-eosin stain) shows a necrotising granulomatous lesion with focal vascular destruction.
Fig. 2 MRI of the left upper extremity demonstrating focal cortical destruction on the lateral aspect of the proximal humerus (white arrow) and a 2.6×0.8×3-cm fluid collection anteriorly (black arrow); 279×123 mm (96×96 DPI).
This new irradiation method could be useful for any brain disease where extremely precise focal tissue destruction is required.
One participant had a smaller tumour but with focal cortical destruction.
In addition, mice possessing the null mutation for RANKL are protected from focal bone destruction in the serum transfer model of inflammatory arthritis.
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