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Intact MDCK cells were observed in close proximity to the damaged areas, suggesting a focal damage of the cell monolayer related to a contact-dependent trophozoite-target cell interaction.
Cardiomyopathy in mice lacking gamma-sarcoglycan or delta-sarcoglycan is characterized by focal damage.
The neural substrates of motor recovery after focal damage to the central nervous system.
Blizzard, C. A. et al. Focal damage to the adult rat neocortex induces wound healing accompanied by axonal sprouting and dendritic structural plasticity.
This review maps out the attempts to describe functionally relevant adaptive changes in the human brain following focal damage.
In the third stage, the spirochete invades the nervous system and may cause tabes dorsalis (see above The spinal cord: Inflammation) or chronic syphilitic encephalitis, which causes progressive dementia and signs of focal damage to the brain.
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Adult skeletal muscle cells are also able to repair focal damages induced by muscle contraction to the sarcolemma or myofibrils, with no inflammatory reaction and preservation of the histological features.
After only 2 hrs of exposure, significant multi-focal damage to gill tissues was apparent.
Thus, non-focal damage to hindwings creates an artificial sink that then produces an ectopic eyespot.
Furthermore, it is difficult to believe that non-focal damage to forewings produces a morphogen source, whereas non-focal damage to hindwings produces a morphogen sink in J. coenia (and not necessarily so in other species).
A similar model was proposed for B. anynana in which non-focal damage to dorsal forewings creates a morphogen sink and, consequently, an ectopic eyespot [ 3- 5].
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