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This measure reflects chemical connectivity of a focal compound [ 33].
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The searching algorithm of theodolite auto-focusing based on compound focal judgment can eliminate disturber effectively, avoid the local undulation of the focusing estimation function, and improve the auto-focusing reliability by combining the common images definition estimation function and MTF value of images.
The source is imaged at the focal point of a compound magnetic lens array.
VCs originating from SAR-informative matrices represent natural focal points for interactive compound design.
Bioavailability of resveratrol is one of the focal points because the compound is poorly bioavailable, low water soluble, and chemically unstable [ 69, 90].
A compound auto-focal judgment combining image definition evaluation function and modulation transfer function (MTF) auxiliary function was introduced to improve the hill-climbing method.
All of these compounds increase focal adhesion stability to inhibit productive cell motility [11], [13].
The imaging findings highlighted a different neuroanatomical pattern of functional inhibition for the two compounds: GSK1059865 produced focal striatal effects, whereas JNJ1037049 induced a composite pattern of modulation characterised by a prominent cortical involvement.
Activity cliffs represent centers of SAR discontinuity in activity landscapes of compound datasets and are focal points of SAR exploration [31].
Since phloretin inhibited the induction of c-Src and kinases pivotal in organizing the cell's cytoskeleton, one can assume that this compound can encumber reorganization of focal adhesions and cell migration.
Some current focal points of interest here include nitroso compounds, DNA topoisomerase inhibitors, viruses, anti-AIDS drugs, and endocrine disruptors.
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