Sentence examples for focal base from inspiring English sources
"I had an uncle who had a saloon on Seneca Street that was a focal base for politics -- Fuzzy Molloy, of all names," he told The Buffalo News.
Different base substitutions occurring on the focal base of all possible 64 contexts on each replichore were called.
We measured the significance of asymmetry of the focal base between 500 positions upstream and downstream of nucleocyclic (or, non-nucleocyclic) TSSs using a two sample z-test of the null-hypothesis that the average base incidences upstream and downstream are equal.
Then we multiplied the expected number of nucleotides by the average genomic mutation rate, to give the GC normalized mutation rate (U), which was used to plot the topology: U = (U 1 μ ¯ 1 + U 2 μ ¯ 2 ) × μ. "Context" refers to the single 5′ and 3′ flanking bases on the same strand as a focal base, recognizing that a G C base pair is not equivalent to a C G base pair.
By contrast, proofreading may be less efficient when focal bases are flanked by a G or C. G/C nucleotides stabilize the pairing between strands and may thereby facilitate mismatched base pairs, as a mismatch will be less likely to destabilize the helix sufficiently to trigger proofreading.
One could argue that the current study's findings depend on accurate classification of ProM cues as focal vs. non-focal based on McDaniel and Einstein's description of the characteristics of these cues, and that McDaniel and Einstein would classify the cues differently.
Against such a disengaging relationship with things in the world Borgmann argues for the importance of focal practices based on focal things.
We also evaluated the variety of the focal mechanisms based on the Kagan angle (1991) from the reference focal mechanism.
Focal Communications, based in Chicago, came out of bankruptcy protection in July and is now EBITDA positive.
Triangle diagrams (Frohlich 2001) show the distribution of focal mechanisms based on the dip angles of the P-, T-, and N-axes.
The architecture also supports users' browsing with the interface by automatically assigning proper focal points, based on information embedded in the debugged programs.
