Sentence examples for focal assembly from inspiring English sources

It is necessary, therefore, to understand cellular processes within the context of intranuclear microenvironments that mediate the focal assembly of the machinery for transcription, replication and repair and which facilitate the orchestration of these essential processes.

Or there could be focal assembly and disassembly of lamin dimers that form the filaments, a model that has been proposed for cytoplasmic intermediate filaments [47].

These findings provide a molecular explanation for the MDC1 MRN interaction and yield insights into how MDC1 coordinates the focal assembly and activation of several DDR factors in response to DNA damage.

Consistent with these data, we observed that Mic60 localizes to focal assemblies in ∆ mic19 cells.

An equivalent current dipole (ECD) model provides an excellent approximation to localize such focal assemblies of active pyramidal cells [ 23].

On the other hand, Figure 7C shows that Mic60 forms focal assemblies in Mic19 null cells that overlap with Mic27.

We considered Mic19 as it has a functional relationship to each MICOS subcomplex; Mic19 disperses Mic60 foci in ∆MICOS and the absence of Mic19 specifically results in the formation of Mic27 focal assemblies in cells.

Our data provide evidence that EPM guides MO of WB-F344 cells via effects on stress fiber bundles and focal adhesion assembly, as supported by blockade EPM, β1 integrin, and F-actin assembly.

Recent evidence supports a prominent role for NHE1 in coordinating motility [ 6- 9] by selectively regulating cytoskeletal events such as focal adhesion assembly and turnover, cortical cytoskeleton dynamics and tyrosine phosphorylation of focal adhesion kinase, with consequent impaired recruitment and assembly of integrins, paxillin and vinculin at focal contacts [ 41].

The RLS focal plane assembly incorporates a charge coupled device (CCD), a thermal/mechanical interface (cold finger) and proximity electronics.

The design and performance of a focal plane assembly consisting of a linear detector and ASICs is reported here.