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Briefly, FBA yields a single flux solution that satisfies specified objective and constraints based on linear program (LP) optimization.
The flux solution incorporates power iteration with two different acceleration techniques: coarse mesh rebalancing (CMR) and coarse mesh finite difference (CMFD).
A full core simulation code includes steady state and transient neutron flux solution capabilities together with reactor operation, micro depletion, and simplified thermal-hydraulics models.
By using a high temperature solution method, the so-called "flux method", and by choosing an appropriate chemical composition of the flux solution, we obtained periodically domain-structured KTP layers with thicknesses up to 800 μm and regular periodicity onto (001) and (001̄) faces of the initial PPKTP seeds.
A final consideration when using genome scale models is the method used to determine a flux solution.
Other approaches however identify the solution that minimises the amount of metabolic adjustment from another flux solution [24] or minimising the number of on/off reactions between two solutions [25].
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The second screen entails determining whether the analytes provide unique flux values or multiple flux solutions.
Most existing borehole heat exchanger models are based on constant heat flux solutions.
After obtaining the flux bounds via MILP, analytes are first screened for whether the predicted NMR spectra associated with various analytes can differentiate between different extreme point (or linear combinations of extreme point) flux solutions.
Highly similar flux solutions were computed using either a model with undefined pathway localization or a model with constraints based on curated (S. cerevisiae) or computationally predicted (H. polymorpha) localization information, while false solutions were found with incorrect localization constraints.
Statistical significance between flux solutions for the analysis of alternate flux solutions was determined by use of 1-way ANOVA.
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