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Therefore, the flux control mechanism is artificially exploited to control the congestion at the bottleneck.
To analyse the impact of GBE on metabolic states of mitochondrial respiration, two flux control ratios have been evaluated.
(A ) Schematic of experimental flux control analysis.
The sum of the partial flux control coefficients for all intermediates equals the flux control coefficient.
The sum of the partial flux control coefficients over all intermediates equals the flux control coefficient.
Partial flux control coefficients can be obtained by partitioning flux control coefficients.
10.7554/eLife.03342.006 Figure 4. Experimental flux control coefficients.
The largest flux control was observed with inhibition of GAPDH.
A unified picture of flux control in aerobic glycolysis.
An analysis of the flux control revealed several interesting responses.
These genes are termed HFC for high flux control.
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