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To test this idea, we measured the membrane fluidity of cells stably expressing IFITM1 using fluorescence recovery after photobleaching (FRAP).
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The permeability and fluidity of cell membrane depended on the saturability of the containing fatty acid (Wang et al. 2013).
The cholesterol transport between cells is influenced by the fluidity of cell membranes and the distribution of microdomains such as lipid rafts.
High levels of unsaturated fatty acids, such as oleic, linoleic, and linolenic acids, are present in plant oils and maintain the fluidity of cell membranes.
The addition of olefinic double bonds of unsaturated fatty acids may also be the reason to decrease the fluidity of cell membranes.
Filipin is a polyenic antibiotic that binds to cholesterol and thus interferes with the fluidity of cell membranes.
The hydroxyl radicals can cleave cell wall polysaccharides such as xyloglucan and pectins, potentially increasing the fluidity of cell wall polymers and enabling cell expansion [ 87, 88].
In the presence of Fe2+ ions H2O2 is converted into highly reactive hydroxyl radicals (OH), which via peroxidation of membrane lipids affect the fluidity of cell membranes.
Lipid peroxidation changes the fluidity of cell membranes, reduces the capacity to maintain an equilibrated gradient of concentration, and increases membrane permeability and inflammation [ 6].
However, we are not aware of human studies investigating the relevance of alterations of the fluidity of cell membranes for the incidence of type 2 diabetes.
These compounds are potentially harmful to cells, causing damage by inactivating proteins, breaking nucleic acid strands, and altering the lipids and fluidity of cell membranes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com