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In summary, our results suggest that the transition of Lα (Figures 4a & 4b) to Im3m (Figures 4c & 4d) as a result of membrane fusion processes [21], [52], [53] takes place through the interplay of the following steps: (1) enhancement of the lipid chain fluidity, (2) water uptake, and (3) penetration of F127 into the membrane surfaces.

Thus, an enhancement derived from decreased membrane fluidity of shedded liposomes may be masking the full impact that decreased delamination from LCMPs has on humoral antibody responses.

The CAF-triggered increase in SCD1 expression is consistent with the CAF-mediated enhancement of cancer cell membrane fluidity and migration that we have previously demonstrated (Angelucci et al, 2012).

In accordance with the formerly demonstrated enhancement in cancer cell membrane fluidity induced by NFs or CAFs (Angelucci et al, 2012), here, we report the ability of fibroblasts to upregulate SCD1 expression.

Previous investigations on the mechanism of transdermal permeation of phospholipid microemulsion indicate that phospholipids mainly increased the fluidity of the intercellular lipids of the stratum corneum, which led to enhancement of percutaneous permeation of drugs [49, 53].

There are also various reports about permeation enhancements of sulfoxides like DMSO [ 19, 21, 22], which can increase lipid fluidity and promote drug partition [ 23, 24] or polyols like PG [ 17, 25, 26], which are described to solvate α-keratin and occupy hydrogen bonding sites [ 27, 28].

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He clearly loves fluidity.

"I wanted constant fluidity.

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