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The duration and intensity of these actions could be modulated through manipulation of liposome characteristics (membrane fluidity and surface, vesicle size and peptide-to-lipid ratio), the most prolonged effects being produced by pegylated, rigid and calibrated liposomes.
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Additional factors that may contribute to the selective killing of cancer cells by ACPs include membrane fluidity and cell surface area.
These phospholipids contribute an important structural role to the membrane and, in addition, determine membrane fluidity and cell-surface charge.
Differences in cell membrane composition, fluidity [ 52] and surface area [ 53, 54] between cancer cells and normal cells may be factors that make the former cells more susceptible to the peptides.
Refinement of the lipid composition to tune fluidity, surface charge density, and surface hydration resulted in vesicles that adsorb fewer proteins from serum and thus are less readily recognized by the immune system.
Membrane fluidity estimations using 1,6-diphenyl-1,3,5-hexatriene (DPH), 1-[4- trimethylammonio phenyl]-6-phenyl-1,3,5-hexatriene (TMA-DPH) indicated no changes in core and surface membrane fluidity following ammonium acetate administration.
Given the chemical and compositional diversity of biological membranes, and their differing physical properties including thickness, fluidity, curvature, lateral pressure, bilayer coupling and surface charge, they constitute highly specialized environments.
The results showed that with the increase in Na2C03 content, melting temperature, viscosity and viscous activation energy of mould flux decreased obviously, fluidity increased, surface tension changed little, and A1203 inclusion adsorption of mould flux increased.
We have shown that adaptation can allow E. coli to be more tolerant of SCFAs (Fig. 1e) by maintenance of the optimal membrane fluidity and possibly by restructuring of the membrane composition and surface properties, such as hydrophobicity.
The effects of particle size and surface property of different spherical silica on the fluidity of resin materials were conducted.
The refractory surface temperature, molten slag fluidity, and molten slag flow rate have a significant impact on the refractory brick corrosion rate.
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