Your English writing platform
Discover LudwigSuggestions(1)
Exact(9)
Recommendations uniformly suggest initiating aggressive fluid resuscitation using either crystalloids or colloids with the addition of catecholamines in cases of fluid refractory shock [1, 6].
Whereas fluid refractory hypotension is generally treated with a single agent (a vasopressor), hypertension can be treated with a large array of drugs.
Another RCT conducted in 102 children with severe sepsis or fluid refractory shock reported similar results (mortality: 11.8% versus 39.2% in controls) [85].
Eighty percent of the children with fluid refractory septic shock present with a low cardiac index.
The focus was on fluid responsive rather than fluid refractory shock, and the relevance of this meta-analysis to children requiring inotropic support is uncertain.
Recommendations uniformly suggest initiating aggressive fluid resuscitation using either crystalloids or colloids with the addition of catecholamines in cases of fluid refractory shock [ 1, 6].
Similar(51)
This suggests that few patients were declared to have fluid-refractory or vasoactive-dependent septic shock in the first hours after presentation to the ED.
The 2012 Surviving Sepsis Guidelines recommend that vasopressor support be started for fluid-refractory shock as part of the 6-hour bundle based solely on expert opinion [ 15].
A related limitation is that we did not determine whether PICU sepsis patients initially presented with obvious fluid-refractory or vasoactive-dependent sepsis making a biomarker unnecessary.
Fluid overload refractory to loop diuretic therapy can complicate acute or chronic heart failure (HF) management.
Renal replacement therapy (RRT) is frequently used in the ICU for patients with acute renal failure, fluid overload, refractory metabolic acidosis or intoxication.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com