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The fluid mosaic model of Singer and Nicolson in 1972 shows how proteins are embedded in membranes.
In 1972, Singer and Nicolson developed the fluid mosaic model to explain the composition of the cell membrane bilayer with randomly oriented globular proteins and lipids [16].
In 1972, Singer and Nicolson made the important distinction between integral and peripheral membrane proteins in the fluid mosaic model of biological membranes[14].
Usual type of widely accepted structure of cell membrane is fluid mosaic model with outward and inward projection of polar heads and non-polar heads with several embedded globular proteins.
Analysis of the binary SA/BSA mixed monolayer confirms the spontaneous interaction between integral proteins and the lipids in accordance with the fluid mosaic model of Singer and Nicolson in 1972.
All modern cells are bounded by cell membranes best described by the fluid mosaic model.
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Indeed, cell membrane is composed of a mixture of phospholipids in a fluid phase and as such, in the classical fluid-mosaic model of membrane [ 15], membranes components undergo isotropic random movement akin to Brownian motion [ 16, 17].
My historical account supports this synthetic interpretation, as it shows that several mosaic models predated Singer and Nicolson's hypothesis; the final acceptance of the fluid mosaic did not result from a novel change of perspective, but from the accumulation of supportive data from diverse experiments.
This order takes the form of a "fluid mosaic" of molecular association complexes of both lipids and proteins in the membrane plane.
Electron crystallography has played a vital role in advancing our understanding of proteins in membranes since the 'fluid mosaic model' was proposed in 1972.
A "landscape mosaic" model was a temporal model of the shifting landscape mosaic, based on the probability of landscape mosaic change for all pixels.
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