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Results: Crystalloids (n = 356) or colloids (n = 385) were administered for all fluid interventions other than fluid maintenance throughout the ICU stay.
In line with this concept, we designed an intraoperative fluid management protocol where minimal fluid maintenance with a crystalloid solution (fluid restriction) was combined with the administration of fluid boluses in case of severe and documented hypovolemia.
We therefore designed an intraoperative fluid management protocol where minimal fluid maintenance with a crystalloid solution (fluid restriction) was combined with the administration of fluid boluses only in case of severe hypovolemia defined by the association of a low cardiac index with a high SVV.
In the GDFR group, (1) fluid maintenance was restricted to 3 ml/kg/h of a crystalloid solution and (2) colloid boluses were allowed only in case of hypotension associated with a low cardiac index and a high stroke volume variation.
In the GDFR group and during surgery, fluid maintenance was set at 3 ml/kg/h of normal saline with an infusion pump, and additional colloid (gelatins or hydroxyethyl starches) boluses (200 ml) were allowed only in case of systemic hypotension (MAP < 65 mmHg) with a cardiac index (CI) <2.5 l/min/m2 and a stroke volume variation (SVV) >15%.
Interventional studies have compared restrictive regimens of fluid maintenance using more liberal strategies.
Similar(33)
During the first week of ICU admission, the excess of fluids seems to be caused by hidden fluids (maintenance and drug-related fluids).
The patient was managed with intravenous fluids, maintenance haemodialysis (eight cycles), antibiotics and other supportive care.
After a bolus of normal saline (20 mL/kg) and following 48 h of intravenous fluids (maintenance rate), urine PGE2 excretion decreased to normal ranges in both siblings (Case 1: 374 ng/24 h/1.73 m, Case 2: 312 ng/24 h/1.73 m in Case 2).
Life cycle cost models used in case studies are compared to an empirical model, used at the company, where dynamic energy, fluid, and maintenance cost are included.
Treating physicians used the study fluid for maintenance; infusion rate and the use of additional fluids were left to their discretion.
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