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ANOVA models are usually used to test if there is a significant difference among the mean values, so it is not robust to inconsistent fluctuations of expression values.
Glyma12g34550 (BURP domain-containing protein) was up-regulated during midday (3.14 fc) and pre-dawn periods (2 fc), however, the diel fluctuations of expression were significant only in control plants (Fig. 7g, Additional file 8).
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The purpose of this study was to investigate the fluctuation of expression and activation of mitogen-activated protein kinase in normal human endometrium throughout the menstrual cycle.
If the fluctuation of expression values is low, corresponding to small σ(p), S1(p) plays a more important influence on the active threshold.
The null hypothesis here is that the Alu-carrying RNA duplex cannot trigger subsequent post-transcriptional regulation, manifesting a random fluctuation of expression levels.
Furthermore, these final genes present expression ranges wide enough so the fluctuations of their expression dependences can be analysed.
One fact with profound consequences in the cell fate decision is the metastable gene expression patterns originating from the random fluctuations of the expression of individual genes.
Likewise we observed fluctuations of GAPDH expression within our experimental setup.
In such scenario, autoregulation not only contributes to the precise integration of environmental states, but can also avoid noisy fluctuations of TF expression [5].
In culture, isogenic mammalian cells typically display enduring phenotypic heterogeneity that arises from fluctuations of gene expression and other intracellular processes.
Second, there is evidence, that stochastic fluctuations of gene expression levels potentially have a functional role and contribute to cellular stability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com