There may be day to day fluctuations in severity with long plateaus between events (Erkinjuntti 1999).
It would be reasonable to assume that general ward admissions are less likely to be affected by fluctuations in severity by day of week, although we are unable to confirm this through the data available to us.
This is based on evidence of a fine amplitude, regular frequency tremor, of at least 6 8 Hz, with a unidirectional axis, that was present during action and exhibited rapid fluctuations in severity.
Diurnal fluctuation in the severity of the dystonia is common, though this may abate with age.
Furthermore, the definition of a responder (≥ 2-point decrease in IGA score) may not have been ideal owing to possible spontaneous fluctuation in ichthyosis severity and low sensitivity of a subjective 5-point scale.
The latter is characterized by a variable age of onset and shows a greater temporal fluctuation in symptom severity, and these individuals might not eventually develop full-blown psychosis.
The variation in severity of illness and prescribed medications throughout the ICU course may lead to fluctuation in GE in critically ill patients over time.
Participants described fluctuations in the severity of some RSV symptoms between daytime and nighttime hours, leading them to endorse the assessment of symptoms over 12-h time periods.
This method may be more at risk of being influenced by natural fluctuations in CM severity, however, in our cohort of highly refractory patients such fluctuations were not commonly seen prior to ONS.
