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The fluctuation in expression of these genes that are involved in carbon metabolism likely represents a response to the differences in carbon source [30], [40].
Cheng and Church tried to identify submatrices of low mean residue score which indicates uniform fluctuation in expression profiles.
When transcriptional regulation genes were also expressed by the multipotent BM-MSC or the liver, there was wide fluctuation in expression levels between cell types, which was not the case for the hNCC hES comparison.
Comparing the two tasks, foragers show a significantly higher correlation to the predicted daily fluctuation in expression levels of foraging than nest workers (t = 2.72, r = 0.74, p = 0.03).
Using real time qPCR analyses with a harvester ant ortholog to foraging (Pofor), we found that the brains of harvester ant foragers have a daily fluctuation in expression of foraging with mRNA levels peaking at midday.
This fluctuation in expression levels between cuticle proteins containing the same domain type and the presence of various domains in cuticular proteins indicates that numerous genes are involved in the formation of the crustacean exoskeleton, that they are not up-regulated simultaneously, and that each may have a distinct role in cuticle formation.
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Here we use microarray gene expression profiling and analysis to compile a set of 1,522 high quality HKGs that are highly expressed in 42 normal tissues and show minimal fluctuations in expression level across these tissues.
Metabolic pathways in cells must be sufficiently robust to tolerate fluctuations in expression levels and changes in environmental conditions.
Synthetic gene regulatory networks show significant stochastic fluctuations in expression levels due to the low copy number of transcription factors.
These mechanisms operate at two levels: one is the molecular crosstalk between effectors and enzymes; and the other is gene expression, where the relationship between fluctuations in expression and network performance is still poorly understood.
Using quantitative PCR, we measured fluctuations in expression of these clock genes over both diel and monthly spawning timeframes.
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