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The latter regions also appear as hot spots; i.e. high frequency fluctuating regions, of the structure surviving in unfolded conformations.
The identification of rare-conformational transitions as well as collectively fluctuating regions in the protein is of functional importance.
The advantages of this nanopore for the exploration of the quasithermodynamic contributions to protein fluctuations include the following: (i) The high-resolution, X-ray crystal structure of the OccK1 protein is now available, permitting rationally designed modifications of the fluctuating regions (e.g., the extracellular loops).
Moreover, the mutations were differently distributed between ordered and highly fluctuating regions.
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An interesting feature is that the graphic curves which reflect the dynamic responses of the steel-concrete composite beam-train interaction system under the influence of the slip can be divided into two regions (fluctuating area and smooth area), and there is an obvious critical value (0.8 × 106 N/m) between the two regions.
Around the same time, BOLD resting state networks (RSNs), which represent coherently fluctuating brain regions observed in the resting human brain, became a topic of major interest (Biswal et al. 1995; Lowe et al. 2000; Cordes et al. 2001; Greicius et al. 2003; Fox et al. 2005; Damoiseaux et al. 2006; De Luca et al. 2006; Smith et al. 2009; Laird et al. 2011).
The mou, a unit of land measure, fluctuated from region to region from 0.08 to 0.13 hectare (0.2 to 0.3 acre).
Also addressed by Gueymard and Wilcox was the magnitude of the inter-annual variation, which was found to fluctuate from region to region.
The nucleotide diversity of human genome sequence appears to fluctuate from region to region [ 3- 5].
Compared to Burgundy, New Zealand pinot noir has a name for consistency, a blessing and a curse: the implication being that it avoids the troughs and the peaks of the fluctuating French region.
Intensity particularly fluctuates in regions immediately posterior to the MF.
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