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They have identified three genetic variants of SFTPA2 that associate with flu severity (rs1965708-C, rs1059046-A, and haplotype 1A) and one with protection (1A).
Although the idea of delivering a single recombinant protein to improve flu severity may appeal to many of us, we must be mindful that IAV has incredible potential to acquire genetic mutations randomly and under intense selective pressure.
Comparing genotypes for measures of poor lung function, inflammation, and admission to intensive care, these authors identified three variants of the SP-A gene SFTPA2 that positively correlated with flu severity.
It is possible that some of the genetic variants identified by the current group are subject to different rates of protein turnover in the lungs, with downstream effects on flu severity.
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Consider asking your doctor to prescribe one of the two approved antiviral medications that can help reduce the flu's severity and duration.
Even as cases of the disease are confirmed in more and more countries Germany and Austria have just been added to the list the flu's severity is in question.
They had only half of the volunteers read a passage about swine flu, its severity, and a shortage of the highly recommended vaccine.
In fact, the new H1N1 virus is similar to seasonal flu in its severity.
Note the Flu-iiQ was previously two measures, the Influenza Symptom Severity scale (ISS) and the Influenza Impact Wellbeing Scale (IIWS).
3 It was specifically designed to target more than one factor influencing behaviour: first, the text message represents a recommendation from the general practitioner (GP); second, it indicates the severity of flu and that the patient is susceptible to flu; third, it acts as a prompt to patients who might have simply forgotten to make an appointment.
Two existing antiviral drugs—oseltamivir (Tamiflu), a pill, and zanamivir (Relenza), a nasal spray were likely to be able to shorten the duration and severity of flu caused by an H5N1 influenza strain if they were used soon after a person became infected.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com