The Semantic Reef Knowledge Representation system is an eco-informatics application designed to assist in the integration of remotely sensed data streams and historic data sets supporting flexible hypothesis design and knowledge extraction.
We provide a solution that allows relatively quick (∼3.5B reads from 238 sequencing lanes providing 81× average coverage of a 3 GB human genome, processed in 12 hrs) and flexible hypothesis testing that is targeted to a genomic region of interest, whether it comprises a fusion, translocation, SNV or SNP.
Such awareness based on this more flexible hypothesis, in turn, may lead us to reconsider the framework of clinical diagnosis of PD to enhance the clinical recognition of the wider spectrum of LB disease not restricted to PD or DLB [ 11, 12].
Finally, the data substantially favored the strong flexible allocation hypothesis over the weaker flexible allocation hypothesis (C versus B), by a factor of 6 to 1. Overall, the data provide substantial evidence in favor of the flexible resource allocation hypothesis.
The Bayes factor for the broadly flexible allocation hypothesis (B exclusive of C) versus the inflexible allocation hypothesis (A exclusive of B and C) was 19, meaning that the data favored the flexible allocation hypothesis by 19 to 1, considered strong evidence against the inflexible allocation hypothesis (Jeffries, 1961).
The inflexible allocation hypothesis was rejected even more decisively against the strong flexible allocation hypothesis (that is, C versus A); this Bayes factor was 53, which is considered very strong evidence.
The flexible distribution hypothesis implies a regulation of the distribution of produced hormones between maternal circulation and yolk and would explain a negative correlation between ovarian hormones in eggs and females' plasma.
In the case of repeated colonizations of similar environments from the same source population this "flexible stem" hypothesis predicts similar phenotypes to arise in repeated subsequent radiations.
The beta distribution is limited to values between 0 and 1 providing the most flexible null hypothesis, and most stringent test, for testing positive selection.
But since there is a considerable chance of the Lake Masaya A. citrinellus population being very young and since plasticity here seems not be lost easily (at least not over several generations), we suggest that our results endorse the "flexible stem" hypothesis for the Midas Cichlid assemblage.
